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TxPert: using multiple knowledge graphs for prediction of transcriptomic perturbation effects
Nature Biotechnology, Published online: 01 May 2026; doi:10.1038/s41587-026-03113-4
TxPert predicts unseen single transcriptomic perturbations with accuracy approaching split-half experimental reproducibility.
Intellia Therapeutics’s Senior Vice President Maria Natale discusses why the most successful launches are shaped long before approval, with strategy, structure and patient insight at the core.
DemeRx is launching the first U.S. clinical trial of an ibogaine-derived drug candidate, marking a pivotal moment for a controversial psychedelic long sidelined by safety concerns.
After suffering the market withdrawal of its only product, Amylyx is gearing up for a pivotal Phase 3 readout in post-bariatric hypoglycemia. But the company’s driving ethos is still to treat “debilitating, devastating” neurodegenerative diseases, co-CEO Justin Klee told BioSpace.
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