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How does ibogaine work? Understanding matrix logic to make a safer drug

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Ibogaine’s unconventional “matrix pharmacology” may underlie both its therapeutic promise and unpredictable cardiac risks. Unraveling this mechanism could help drug developers hoping to bring ibogaine analogs to market.

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Celiac disease is entering a new era of therapeutic innovation

For the ~1 in 100 people living with celiac, the burden of disease extends far beyond their plate.

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For the ~1 in 100 people living with celiac, the burden of disease extends far beyond their plate.

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The commercial launch playbook: Team structure, readiness and execution

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Intellia Therapeutics’s Senior Vice President Maria Natale discusses why the most successful launches are shaped long before approval, with strategy, structure and patient insight at the core.

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Despite FDA trial clearance, ibogaine metabolite won’t receive red carpet treatment

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DemeRx is launching the first U.S. clinical trial of an ibogaine-derived drug candidate, marking a pivotal moment for a controversial psychedelic long sidelined by safety concerns.

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