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STAT+: Pharmalittle: We’re reading about an FDA review of Moderna’s flu shot, J&J’s focus on cancer, and more

And so, another working week will soon draw to a close — at least on this side of the pond where we have a holiday tomorrow. This means we are staring down a longer-than-usual agenda to fill. So far, we plan to manicure the Pharmalot campus and promenade extensively with the official mascots, and we hope to hold still another listening party, where the rotation will likely include this, this, this, this and this. And what about you? The great outdoors, as always, is beckoning, which could mean a jaunt to the beach or perhaps a hike in the woods. Or maybe a stroll along city streets with an iced drink in hand. If the weather fails to cooperate, the great indoors also provides comfort — you can cook a favorite meal, curl up with an e-book, or binge-watch the telly. Well, whatever you do, have a grand time. But be safe, enjoy, and see you soon. And if dad is still around, remember to say hello. …

Johnson & Johnson has no plans to enter the booming obesity market, opting instead to focus on diseases such as cancer, Bloomberg News writes. This sets J&J apart from many of its rivals trying to develop or acquire obesity medicines following blockbuster weight loss drugs from Eli Lilly and Novo Nordisk. J&J chief executive officer Joaquin Duato said the company aims to become the world’s leading cancer company, with oncology as one of its core growth pillars. Last year, J&J paid $3.05 billion in cash for Halda Therapeutics, gaining access to an innovative new type of oral therapy for prostate cancer. His remarks come as J&J continues to reshape itself following the spin off of its Kenvue consumer health business.

The U.S. Food and Drug Administration approved GSK’s oral antibiotic to treat complicated urinary tract ​infections, giving patients a new treatment option ‌against drug-resistant infections, Pharmaphorum notes. While the pill, called Utebzi, does not offer a novel mechanism of action, it provides an alternative to the current intravenously administered carbapenems, which are often used as a last resort for infections resistant to other antibiotics. GSK acquired rights to Utebzi in a $591 million licensing deal in 2022 with Spero Therapeutics, just a few months after the FDA rejected Spero’s first marketing application for the antibiotic with a request for an additional clinical trial.

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And so, another working week will soon draw to a close — at least on this side of the pond where we have a holiday tomorrow. This means we are staring down a longer-than-usual agenda to fill. So far, we plan to manicure the Pharmalot campus and promenade extensively with the official mascots, and we hope to hold still another listening party, where the rotation will likely include this, this, this, this and this. And what about you? The great outdoors, as always, is beckoning, which could mean a jaunt to the beach or perhaps a hike in the woods. Or maybe a stroll along city streets with an iced drink in hand. If the weather fails to cooperate, the great indoors also provides comfort — you can cook a favorite meal, curl up with an e-book, or binge-watch the telly. Well, whatever you do, have a grand time. But be safe, enjoy, and see you soon. And if dad is still around, remember to say hello. …

Johnson & Johnson has no plans to enter the booming obesity market, opting instead to focus on diseases such as cancer, Bloomberg News writes. This sets J&J apart from many of its rivals trying to develop or acquire obesity medicines following blockbuster weight loss drugs from Eli Lilly and Novo Nordisk. J&J chief executive officer Joaquin Duato said the company aims to become the world’s leading cancer company, with oncology as one of its core growth pillars. Last year, J&J paid $3.05 billion in cash for Halda Therapeutics, gaining access to an innovative new type of oral therapy for prostate cancer. His remarks come as J&J continues to reshape itself following the spin off of its Kenvue consumer health business.

The U.S. Food and Drug Administration approved GSK’s oral antibiotic to treat complicated urinary tract ​infections, giving patients a new treatment option ‌against drug-resistant infections, Pharmaphorum notes. While the pill, called Utebzi, does not offer a novel mechanism of action, it provides an alternative to the current intravenously administered carbapenems, which are often used as a last resort for infections resistant to other antibiotics. GSK acquired rights to Utebzi in a $591 million licensing deal in 2022 with Spero Therapeutics, just a few months after the FDA rejected Spero’s first marketing application for the antibiotic with a request for an additional clinical trial.

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New biotech cAMPfield emerges with $180M to reshape IBD treatment

New biotech cAMPfield emerges with $180M to reshape IBD treatment

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Backed by institutional investors and seasoned industry leaders, cAMPfield Therapeutics is advancing a clinical program aimed at reshaping the landscape for inflammatory bowel disease.​ ​Read More

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STAT+: Shingles vaccine may lower dementia risk, new study finds

If you’re an older adult, getting vaccinated against shingles could lower your risk of developing dementia.

A new study found that elderly nursing home residents who received at least one dose of the shingles vaccine known as Shingrix, the only shot of its kind available in the United States, were 24 percent less likely to develop dementia over a four-year period compared to those who were not vaccinated, according to results published this week in the peer-reviewed journal Annals of Internal Medicine.

The research adds to the growing body of evidence showing a connection between the viral infection and cognitive decline.

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If you’re an older adult, getting vaccinated against shingles could lower your risk of developing dementia.

A new study found that elderly nursing home residents who received at least one dose of the shingles vaccine known as Shingrix, the only shot of its kind available in the United States, were 24 percent less likely to develop dementia over a four-year period compared to those who were not vaccinated, according to results published this week in the peer-reviewed journal Annals of Internal Medicine.

The research adds to the growing body of evidence showing a connection between the viral infection and cognitive decline.

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From fragile skin to living medicine: Lessons from RDEB

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In this episode of Denatured, you’ll hear from Mark Lowdell, CSO & co-founder at INmuneBio Inc. and Vishwas Seshadri, CEO & director at Abeona Therapeutics. We explore how recessive dystrophic epidermolysis bullosa has become a defining case study for gene and cell therapy and what this ultra‑rare disease reveals about the future scalability of advanced therapies.

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