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Immune-remodeling mRNAs expressing IRF8 or NIK generate durable antitumor immunity in multiple cancer models

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May 13, 2026

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Nature Biotechnology, Published online: 13 May 2026; doi:10.1038/s41587-026-03115-2

Immune-remodeling mRNAs delivered in lipid nanoparticles boost antitumor immunity.

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