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AI, Machine Learning & Computational Biology4 weeks agoDesigning Peptide Screens to Generate Knowledge, Not Just Hits
The strongest binder from a primary screen is not necessarily the best drug starting point. Peptide discovery campaigns should capture molecular architecture, biological context, time, and...
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AI, Machine Learning & Computational Biology4 weeks agoAn AI agent made a tiny drug R&D mistake. Then it kept going.
The error points to a big question for pharma as AI gains autonomy and high-profile failures sharpen safety concerns: What happens when a wrong answer becomes...
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AI, Machine Learning & Computational Biology1 month agoAI and Proteomics Accelerate VAV1 Molecular Glue Discovery
High-throughput proteomics combined with AI-based structural modeling helped researchers discover molecular glues that degrade VAV1. The approach could support new therapies for blood cancers and autoimmune...
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AI, Machine Learning & Computational Biology1 month agoGinkgo Datapoints, Apheris Announce Founding Members of Antibody Developability Consortium
The consortium aims to address antibody development bottlenecks by creating standardized datasets and AI models that support earlier risk detection and more informed candidate selection. The...
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AI, Machine Learning & Computational Biology1 month agoAI Tool Helps Link BRSK1 Variants to Neurodevelopmental Disorder
AI-assisted genomic analysis was combined with human genetics and fruit fly experiments to link reduced BRSK1 function to a variable neurodevelopmental disorder. The post AI Tool...
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AI, Machine Learning & Computational Biology1 month agoAccelerated discovery of thermostable mRNA–lipid nanoparticle vaccines using data-efficient AI
Nature Biotechnology, Published online: 28 September 2026; doi:10.1038/s41587-026-03331-wThe thermostability of RNA vaccines is improved with AI.
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AI, Machine Learning & Computational Biology1 month agoAI-guided optimization for thermostable mRNA vaccines
Nature Biotechnology, Published online: 28 September 2026; doi:10.1038/s41587-026-03330-xAGENT, an AI-driven framework integrating high-throughput experimentation with Bayesian optimization, enables the rapid engineering of thermostabl...
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AI, Machine Learning & Computational Biology1 month agoAI Tells Doctors When It Is Unsure About Cancer Treatment Success
Predicting whether a cancer patient will respond to therapy has long been one of oncology’s most consequential gambles. For people with metastatic non-small cell lung cancer,...
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AI, Machine Learning & Computational Biology1 month agoAI Learns to Read Cancer Slides Like a Pathologist by Watching the Neighborhood
Every day, pathologists around the world peer through microscopes at glass slides no bigger than a postage stamp, yet each one can contain billions of pixels...
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AI, Machine Learning & Computational Biology1 month agoAI Language Model Rescues Human Drug Transporter Mutations a Computer Deemed Impossible
Every pill that survives the journey from the stomach into the bloodstream owes much of its success to a single molecular gatekeeper. The human intestinal peptide...
LncRNA SBF2-AS1 Worsens Heart Injury After Attack via miR-149-5p/PHLPP2 Axis
Stigmatizing language found in over half of primary care patient records
Research report: The Influence of Renal or Hepatic Impairment on the Pharmacokinetics of Iclepertin (BI 425809): Results from Two Phase I Open-Label, Non-randomised, Single Dose, Parallel Design Studies
Novartis buys Synnovation’s PI3Kα inhibitors for $3 billion
Novartis to pay $2B upfront to take next-gen PI3Kα inhibitor from Synnovation
