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Mestag raises $40m to advance therapeutic cancer treatment
Mestag Therapeutics has raised $40 million financing to advance its new therapeutic cancer treatment.
The closing of the financing round, led by life science investors SV Health Investors and Johnson & Johnson Innovation, brings total funds raised to over $95 million.
The funding is set to support the Phase I STARLYS clinical study evaluating MST-0312, which is anticipated to start in cancer patients in mid-2026. MST-0312 is a novel FAP-targeted bispecific antibody directed to lymphotoxin-β receptor (LTBR) to induce the formation of tertiary lymphoid structures (TLS) and high endothelial venules (HEV) within solid tumours.
An extensive body of clinical data correlates the presence of TLS and HEV in solid tumours with improved patient survival and enhanced response to therapy. MST-0312 is a potential first- and best-in-class programme pioneering a new therapeutic approach to the treatment of cancer, including tumours that are typically resistant to immunotherapy.
The announcement comes after Mestag appointed Lindsey Rolfe as Chief Medical Officer and Pascal Merchiers as Chief Development Officer.
“We are thrilled to welcome Lindsey and Pascal to the team at this exciting time as we progress our groundbreaking programme MST-0312 into the STARLYS clinical trial,” said Susan Hill, Chief Executive Officer of Mestag Therapeutics.
The post Mestag raises $40m to advance therapeutic cancer treatment appeared first on Drug Discovery World (DDW).
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Sanofi Bispecific Scores in Asthma, Rhinosinusitis, but Eczema Bet Doesn’t Pay Off
Sanofi Bispecific Scores in Asthma, Rhinosinusitis, but Eczema Bet Doesn’t Pay Off
Sanofi has faced questions about the potential of lunsekimig in eczema, with executives calling the clinical trial a “measured risk.” Read More
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STAT+: Gilead to buy cancer biotech Tubulis for more than $3 billion
In a move that will grow its oncology pipeline, Gilead Sciences is spending more than $3 billion to buy the German biotech Tubulis, the companies said Tuesday.
The deal includes an upfront payment of $3.15 billion and up to $1.85 billion more if certain milestones are reached. It also highlights both the therapeutic and commercial promise of antibody-drug conjugates, the next-generation chemotherapy treatments that the privately held Tubulis is developing.
Gilead’s latest move comes just months after it said it would acquire Arcellx in a deal worth $7.8 billion. The two companies had already been working together on a multiple myeloma CAR-T therapy that could be approved later this year. Gilead last month also announced that it was buying Ouro Therapeutics, which is focused on drugs for autoimmune disease, for up to $2.18 billion.
In a move that will grow its oncology pipeline, Gilead Sciences is spending more than $3 billion to buy the German biotech Tubulis, the companies said Tuesday.
The deal includes an upfront payment of $3.15 billion and up to $1.85 billion more if certain milestones are reached. It also highlights both the therapeutic and commercial promise of antibody-drug conjugates, the next-generation chemotherapy treatments that the privately held Tubulis is developing.
Gilead’s latest move comes just months after it said it would acquire Arcellx in a deal worth $7.8 billion. The two companies had already been working together on a multiple myeloma CAR-T therapy that could be approved later this year. Gilead last month also announced that it was buying Ouro Therapeutics, which is focused on drugs for autoimmune disease, for up to $2.18 billion.
In its third acquisition of 2026, Gilead is spending $3.15 billion upfront to snag a next-generation antibody-drug conjugate platform from German startup Tubulis.
The California biopharma could pay out another $1.85 billion down the road …
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