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Jazz strikes new chord with AbCellera in T cell engager pact that could top $2.4B

Jazz strikes new chord with AbCellera in T cell engager pact that could top $2.4B

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Jazz Pharmaceuticals is diversifying its oncology strategy, orchestrating a new antibody deal with AbCellera that offers $56 million upfront, plus $792 million in biobucks for each of the three initial programs.​ ​Read More

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FTC, four state AGs sue transgender health group over care standards

The Federal Trade Commission and four state attorneys general have sued the main professional organization for gender-affirming care clinicians, alleging it made false claims to sell medical services to kids.

The lawsuit against the World Professional Association for Transgender Health, filed Wednesday in a federal court in Texas, is part of the Trump administration’s broader effort to end gender-affirming care for minors. 

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The Federal Trade Commission and four state attorneys general have sued the main professional organization for gender-affirming care clinicians, alleging it made false claims to sell medical services to kids.

The lawsuit against the World Professional Association for Transgender Health, filed Wednesday in a federal court in Texas, is part of the Trump administration’s broader effort to end gender-affirming care for minors. 

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Luigi Mangione will assert psychiatric defense in murder case in UnitedHealthcare CEO’s killing

NEW YORK — Luigi Mangione plans to assert a psychiatric defense at his state murder trial, claiming he was suffering from extreme emotional disturbance when he gunned down UnitedHealthcare CEO Brian Thompson, a judge said Wednesday. That could mean less prison time if he’s convicted.

A jury that accepts such a defense would be obligated to convict Mangione of manslaughter, which carries a maximum sentence of 25 years in prison, instead of murder, which could put him behind bars for the rest of his life. An emotional disturbance defense isn’t available in Mangione’s federal case, where he also faces a possible life sentence.

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NEW YORK — Luigi Mangione plans to assert a psychiatric defense at his state murder trial, claiming he was suffering from extreme emotional disturbance when he gunned down UnitedHealthcare CEO Brian Thompson, a judge said Wednesday. That could mean less prison time if he’s convicted.

A jury that accepts such a defense would be obligated to convict Mangione of manslaughter, which carries a maximum sentence of 25 years in prison, instead of murder, which could put him behind bars for the rest of his life. An emotional disturbance defense isn’t available in Mangione’s federal case, where he also faces a possible life sentence.

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UniQure to file gene therapy for approval, reflecting major shifts at FDA

The decision marks another regulatory U-turn following the exits of Marty Makary and Vinay Prasad, suggesting to some analysts that current FDA leadership may be more flexible in certain cases. 

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The decision marks another regulatory U-turn following the exits of Marty Makary and Vinay Prasad, suggesting to some analysts that current FDA leadership may be more flexible in certain cases. 

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