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Historic FDA approval brings first gene therapy for genetic deafness
Nature Biotechnology, Published online: 28 April 2026; doi:10.1038/s41587-026-03145-w
The first-of-its-kind genetic medicine treats a rare and profound otoferlin-related hearing loss, and will be made available by Regeneron for free in the United States.
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Amgen, AbbVie say IRA negotiations impacted Q1 sales
At least two drugmakers say they’re feeling the impact of the Inflation Reduction Act, after the first drug prices negotiated under the law took effect in January.
Amgen and AbbVie reported in their first-quarter earnings …
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Lilly plans new $4.5B manufacturing investment in Indiana
Eli Lilly is committing to its roots, allocating $4.5 billion for new manufacturing investments across Indiana as drugmakers pledge more US projects.
The world’s largest pharma company, headquartered in Indianapolis,
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STAT+: Administration report on most favored nation drug pricing raises new details — and questions
WASHINGTON — The Trump administration on Tuesday released the most detailed look to date at its drug pricing policy and its purported impact, claiming huge future savings from the program.
The report, from the administration’s own Council of Economic Advisers, lays out the definition of “most-favored nation” pricing. That’s the definition pharmaceutical giants agreed to in their confidential deals with the administration, a White House spokesperson told STAT in an email. The most-favored nation pricing calculation represents a key underpinning of one of the White House’s top election-year talking points — though many key details of the deals remain private, and their ultimate impacts for consumers uncertain.
The analysis estimated the drug companies’ pledge to offer all new drugs at most-favored nation pricing would save the U.S. $529 billion over the coming decade — though the projection comes with big caveats.
WASHINGTON — The Trump administration on Tuesday released the most detailed look to date at its drug pricing policy and its purported impact, claiming huge future savings from the program.
The report, from the administration’s own Council of Economic Advisers, lays out the definition of “most-favored nation” pricing. That’s the definition pharmaceutical giants agreed to in their confidential deals with the administration, a White House spokesperson told STAT in an email. The most-favored nation pricing calculation represents a key underpinning of one of the White House’s top election-year talking points — though many key details of the deals remain private, and their ultimate impacts for consumers uncertain.
The analysis estimated the drug companies’ pledge to offer all new drugs at most-favored nation pricing would save the U.S. $529 billion over the coming decade — though the projection comes with big caveats.
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