Nvidia CEO Jensen Huang asserts that agentic AI systems are driving innovation across industries. At his annual NVIDIA GTC keynote, Huang highlighted OpenClaw, the personal AI assistant that went from a solo developer’s side project to one of the fastest-growing open-source projects in history. 

More researchers are customizing agents for specific use cases. GTC brought together life science leaders to discuss how these advances are transforming biology. 

Andrew Beam, PhD, chief technology officer at Lila Sciences, explains why AI advanced so rapidly in certain domains. The combination of internet-scale data and the rise of transformer architectures enabled the development of large language models. Progress then accelerated in areas that were “easy to verify,” such as mathematics, where proofs can be quickly and objectively evaluated. 

However, science is difficult to interrogate at scale. 

“When you’re talking about the discovery of new knowledge, you need verification,” Beam said. “In science, we call it an experiment.” 

Lila’s aims to build “scientific superintelligence” by scaling the scientific method through autonomous labs. Beam asserts that boosting the throughput of experiments describing the physical world will provide an invaluable data stream for the next generation of AI models. 

Marinka Zitnik, PhD, associate professor of biomedical informatics at Harvard Medical School, adds that agents must be tightly connected to the wet lab, particularly given strong biases in the literature.

“95% of all life sciences publications focus on 5,000 of the most well-studied human genes,” she said. “If our AI agent just reads the literature, there are limitations to the hypotheses that can be generated.”  

Ensuring that agents have access to diverse data modalities—such as molecular structures, single-cell sequencing, and longitudinal clinical trajectories—will be critical to inform actionable experiments for closed loop discovery.  

Rory Kelleher, senior director, global head of business development, healthcare and life sciences at Nvidia, emphasizes that as agent development accelerates, engaging with these frontier technologies will be essential to stay ahead. 

“It’s not that AI is going to replace scientists,” he says, “but perhaps the scientists who use AI are going to phase out the ones who don’t.” 

At GTC, I noted the following agentic systems augmenting the life science lab: 

AI scientist – Kosmos 

Kosmos, the autonomous AI scientist developed by Edison Scientific, reduces human overhead for routine tasks, such as literature searches and data analysis, while performing hundreds of research tasks in parallel to compress months of work into a single day.  

“What’s nice about an AI scientist is decoupling the number of humans using the tool from how much can be done,” said Andrew White, PhD, CTO of Edison. 

The platform’s technical report describes seven discoveries made by Kosmos: three reproduced findings from preprinted or unpublished manuscripts, while the remaining four were novel literature contributions. Among the examples, Kosmos identified a new clinically relevant mechanism of neuronal aging, and generated statistical evidence that high circulating levels of superoxide dismutase 2 (SOD2) may causally reduce myocardial fibrosis in humans. 

Edison is the commercial spinout of FutureHouse, an AI scientist non-profit backed by former Google CEO Eric Schmidt and co-founded by Sam Rodriques, PhD, former group leader at the Francis Crick Institute and Edison’s CEO. Edison serves more than 50,000 researchers worldwide. 

To the physical lab – LabOS 

Le Cong, PhD, associate professor at Stanford University and Mengdi Wang, PhD, professor at Princeton University, have developed LabOS, an AI extended reality (XR) operating system, which unites computational reasoning with physical experiments.  

Recently embedded into “LabClaw” with OpenClaw, the co-scientist connects multi-model AI agents, smart glasses, and robots to allow the platform to understand experimental context and assist in real-time execution.  

LabOS extends the capabilities of CRISPR-GPT, an agentic AI system for CRISPR research, to the physical lab. The XR system is also an answer to science’s reproducibility challenges, where 70% of biomedical scientists cannot reproduce experiments from colleagues, while 50% cannot reproduce their own work after a few months, reports a Nature survey with support from a follow-up study from PLOS. 

Cong is also scientific co-founder of Phylo. Launched in February, the new enterprise is an applied research lab dedicated to agentic intelligence for biomedical scientists.

From text prompt to drug – Latent-Y 

On the heels of GTC, Latent Labs announced Latent-Y, an AI agent that designs therapeutic antibodies from a text prompt. Latent-Y produced lab-confirmed nanobody binders against six out of nine targets, achieving a 67% target-level success rate without human filtering or intervention. Binding affinities reached the single-digit nanomolar range. Additionally, Latent-Y is integrated within the full Latent Labs platform, enabling researchers to audit and query the reasoning traces. 

Simon Kohl, PhD, CEO and founder of Latent Labs, describes the agent as a “force multiplier” that completes design campaigns 56-fold faster than traditional approaches.   

“What’s exciting about science is that we barely run out of ideas,” said Kohl. “We’re constrained by the lab and what’s practically possible. It’s exciting to lift that bottleneck.” 

Additionally, Latent-Y achieves cross-species binder design for translational studies and can generate binders based on a scientific paper input. In one campaign, the agent processed a publication on blood-brain barrier crossing and designed lab validated antibodies targeting human transferrin receptor (hTFR1). 

Filter your binders – Dyno Psi-Phi 

Eric Kelsic, PhD, CEO and co-founder of Dyno Therapeutics, says that agents capable of automating therapy design can reduce costs and foster competition among developers, ultimately offering patients more treatment options. 

Dyno is a genetic medicines company that has spent the past decade addressing the delivery challenge, having developed capsids to target the central nervous system, muscle, and brain. Kelsic emphasizes that the promise of gene therapy lies in the combination of delivery technologies and therapeutic payload design. 

At GTC, Dyno announced Dyno Psi-Phi, a generative and agentic interface for protein binder design. The workflow, developed in collaboration with Nvidia, connects Dyno Psi-1, a molecular model influenced by Nvidia’s La-Proteina family, with Dyno Phi, a collection of filters that select designs most likely to succeed in experimental validation.  

Sam Sinai, PhD, head of machine learning and co-founder at Dyno Therapeutics says much of today’s progress is measured against a narrow set of computational filters, which limits exploration of the broader functional space of proteins.  

“With Psi-Phi, we democratize the filters that work, while introducing models that generate greater diversity and pair naturally with high-throughput experiments,” said Sinai. “Designs succeed not just at binding, but across downstream requirements.” 

Kelsic puts into context that most tools built in recent decades have been for human use. “Agents are now becoming more capable. It’s a new opportunity to build tools that are easy for agents to use,” he said. 

The Psi-Phi platform is accessible through Claude Code to facilitate incorporation into existing AI pipelines. 

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