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Drug Discovery & Therapeutics2 months agoBioNTech sets survival standard in hard-to-treat cancer ahead of pivotal readout
BioNTech has linked gotistobart to a median overall survival of 18.5 months in relapsed lung cancer patients, adding to evidence that the anti-CTLA-4 antibody is better...
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Drug Discovery & Therapeutics2 months ago
Rewriting the rules of genetic medicine with tRNA therapeutics
Our guest today is Dr. Nerissa Kreher, Chief Medical Officer of Alltrna. Nerissa brings two decades of rare disease drug development experience. The post Rewriting the...
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Drug Discovery & Therapeutics2 months agoGenomic diversity and antibiotic resistance in porcine F18 E. coli strains
A team of American researchers has taken one of the most detailed looks yet at emerging strains of enterotoxigenic Escherichia coli (ETEC) circulating on US pig...
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Drug Discovery & Therapeutics2 months agoChronic Interferon Exposure Linked to Immunosuppression in Cancer
A preclinical study uncovered a novel pathway that links chronic IFN-II exposure to mitochondrial dysfunction and ultimately immunosuppression in cancer, creating foundational insights that may point...
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Drug Discovery & Therapeutics2 months agoMonoclonal Antibodies Targeting MMP-9 Alleviate Peripheral Neuropathy in Diabetic Mice
Scientists developed monoclonal antibodies targeting matrix metalloproteinase-9, which in a newly reported preclinical study slowed and even reversed diabetic nerve damage in mouse models of type...
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Drug Discovery & Therapeutics2 months agoKura spins diabetes work into a Lilly-backed biotech startup
Caspian Therapeutics aims to develop menin inhibitors, which have proven effective against leukemia, for diabetes and other cardiometabolic conditions.
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Drug Discovery & Therapeutics2 months ago
Preclinical Pulse: The research catching our eye in September 2026
Find out about seven preclinical assets that caught our attention in the September edition of Labiotech's Preclinical Pulse. The post Preclinical Pulse: The research catching our...
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Drug Discovery & Therapeutics2 months agoDynamic-static multimodal graph learning predicts protein-small molecule binding sites
Every new drug that reaches the pharmacy shelf owes its existence, at least in part, to a deceptively simple question: where, exactly, on a protein does...
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Drug Discovery & Therapeutics2 months agoSTAT+: Leukemia drug data suggested a different way to treat diabetes. A new biotech will test that idea
Caspian Therapeutics, is launching with $50 million in financing to develop menin inhibitors for diabetes and other cardiometabolic diseases.
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Drug Discovery & Therapeutics2 months ago
Precision Medicine Has a Commercialization Problem
As drug discovery is revolutionized by AI, the machinery built to get life-saving medicines to market remains trapped in a different era. Here’s how we solve...
Genmab’s cancer bispecific delivers early survival win in ‘exceedingly positive’ Phase 3 readout
Genmab’s cancer bispecific delivers early OS win in ‘exceedingly positive’ Phase 3 readout
STAT+: HHS moves to allow compounding of some unapproved peptides
Novartis buys Synnovation’s PI3Kα inhibitors for $3 billion
Novartis to pay $2B upfront to take next-gen PI3Kα inhibitor from Synnovation
