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Sequencing peptides by reversing translation

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Nature Biotechnology, Published online: 16 April 2026; doi:10.1038/s41587-026-03108-1

A new peptide sequencing approach converts amino acids into DNA sequences, which are easily read.

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Ionis’ antisense drug stabilizes ultra-rare disease ahead of FDA decision

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The pivotal study of zilganersen in Alexander disease missed a secondary endpoint, but analysts expect the FDA to approve the asset given the unmet need and overall data.

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Lilly exits Rigel alliance, adding to RIPK1 scrap heap

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Eli Lilly and Rigel Pharmaceuticals partnered in February 2021 to advance a pair of RIPK1 blockers, but the pharma in October last year pulled the plug on one of these programs for central nervous system indications.

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Lilly, Novo dip as proposed Medicare coverage for GLP-1 pilot thrown off balance

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Two of the biggest insurance providers have expressed reluctance to participate in the government’s BALANCE program that would have made GLP-1 drugs more affordable to patients.

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