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Fierce Biotech

AstraZeneca delivers dream result as phase 3 COPD hits breathe life into class rocked by flops

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AstraZeneca’s chronic obstructive pulmonary disease drug candidate has hit the mark in a pair of phase 3 trials, delivering broad efficacy with a mechanism that yielded mixed data for Roche and Sanofi.

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Fierce Biotech

Scientists turn pig semen extract into eye drops that kill cancer in mice

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The human eye is like an immunological fortress, with its ability to exclude unwanted intruders a boon when preventing infection but a burden when trying to deliver vital medicines. Researchers in China have now turned to an unusual source—pig semen—to develop eye drops that can deliver cancer drugs to the back of the eye.

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Fierce Biotech

AstraZeneca’s in vivo CAR-T bet eradicates cancer in 3 of 5 patients, but death mars dataset

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AstraZeneca isn’t letting a death in a China trial detract from the potential of its $1 billion in vivo bet, even as the candidate’s safety and efficacy profile have so far failed to separate it from traditional CAR-T therapies.

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Fierce Biotech

After local tumor approval, Novocure touts positive data in metastatic pancreatic cancer

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After collecting an FDA approval earlier this year for local pancreatic cancer, Novocure is putting forward positive clinical data for its electric field-based treatment in metastatic cases of the aggressive disease.

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