BASEL, Switzerland — Pharma manufacturing in Switzerland appears to be unperturbed by the threat of tariffs, but it might take several years before the impact of companies moving production to the US becomes clear.

According to …

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Good morning. I was having a fine day yesterday until my colleague shared this game that tests how good (or how bad in my case) your color perception is.

The need-to-know this morning

• Vertex Pharma reported first-quarter earnings that generally matched consensus, although the company said it was shelving an early stage, mRNA-based therapy for cystic fibrosis due to poor tolerability. The drug, called VX-522, was being developed as part of a collaboration with Moderna. 
• Pfizer and Alkermes also reported earnings.
• Viridian Therapeutics announced positive top-line results from a Phase 3 study of its drug, called elegrobart, in patients with chronic thyroid eye disease.

Cytokinetics drug Myqorzo meets twin efficacy goals in study of genetic heart disease

Cytokinetics said its drug Myqorzo significantly improved heart failure symptoms and cardiovascular fitness in patients with non-obstructive hypertrophic cardiomyopathy, an inherited heart disorder.

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The action affects BioNTech sites in Germany and Singapore, where the company expects to have excess capacity.